Inhibition of Methicillin Resistant Staphylococcus aureus Biofilm by Ethanol Extracts of Sauropus androgynus and Solanum torvum

Sauropus androgynus and Solanum torvum are known to possess antioxidant, anti-cancerous, anti-fungal antiseptic properties. The current study aimed evaluate the effect of ethanol extracts leaves fruit in prevention biofilm formation by methicillin resistant Staphylococcus aureus. also assessed presence bioactive compounds their ability modify cell surface hydrophobicity aureus biofilm. In this study, isolates obtained from tertiary care hospitals Coimbatore were subjected antibiotic susceptibility testing formation. Among 20 isolates, all found be 100 % sensitive vancomycin cotrimoxazole tetracycline. Two observed strong producers confirmed microtiter plate method only one isolate was used for further studies. Phytochemical screening plant materials carried out identify potentially responsible biological tested, showed a maximum zone inhibition (18 mm), whereas exhibited 16 mm at 200 µg/ml against Minimum inhibitory concentration minimum aureus, which each extract 5 mg/ml inhibit growth via method. Moreover, there an increase 33.96 61.90 150 leaves, while 46.80 hydrophobicity. Similarly, anti-adhesive activity higher (0.008) when compared (0.016) 50 µg/ml. reports first time efficacy as promising source anti-biofilm agents, especially